产品货号:
Z12087
中文名称:
BRAF抗体
英文名称:
Anti-BRAF Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BRAF Antibody |
指标别名 | B RAF1;BRAF;BRAF1;p94;Proto oncogene B Raf;RAFB1 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | BRAF |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-B-raf antibody was raised against a peptide corresponding to 19 amino acids near the center of human B-raf.The immunogen is located within amino acids 330 - 380 of B-raf. |
计算分子量 | 84kDa |
成分 | B-raf Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | B-raf Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway,which affects cell division,differentiation,and secretion.The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis.Mutations in B-raf have been associated with several cancers,including non-Hodgkin lymphoma,colorectal cancer,malignant melanoma,thyroid carcinoma,non-small cell lung carcinoma,and adenocarcinoma of lung,leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers.Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS),a disease characterized by heart defects,mental retardation and a distinctive facial appearance. |
Uniprot ID | P15056 |
基因名全称 | V-raf murine sarcoma viral oncogene homolog B1 |
蛋白名全称 | V-raf murine sarcoma viral oncogene homolog B1 |
推荐稀释比 | WB:0.5~2μg/mL;IHC:2.5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索:BRAF抗体,BRAF多抗,Anti-BRAF Antibody